An amyloid disease database for transthyretin mutants
Analysis Tool | Result |
---|---|
iMutant 3.0 | Destabilizing |
STRUM | Stabilizing |
iStable | Stabilizing |
Provean | Deleterious |
PredictSNP | Neutral |
PhD-SNP | Neutral |
PolyPhen-2 | Neutral |
SIFT | Deleterious |
FATHMM | Damaging |
Analysis Tool | Result |
---|---|
mCSM | Destabilizing |
SDM | Stabilizing |
DUET | Destabilizing |
DynaMut | Destabilizing |
CUPSAT | Stabilizing |
ENCoM | Destabilizing |
FoldX (Protein Stability) | Reduces |
Analysis Tool | Result |
---|---|
TANGO (Aggregation Tendency) | No effect |
WALTZ (Amyloid Propensity) | No effect |
LIMBO (Chaperone Binding Tendency) | No effect |